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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREPL
All Species:
22.42
Human Site:
Y169
Identified Species:
44.85
UniProt:
Q4J6C6
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4J6C6
NP_001035844.1
727
83927
Y169
R
V
A
P
D
E
K
Y
V
A
A
K
I
R
T
Chimpanzee
Pan troglodytes
XP_001144400
727
83999
Y169
R
V
A
P
D
E
K
Y
V
A
A
K
I
R
T
Rhesus Macaque
Macaca mulatta
XP_001111959
727
83985
Y169
R
V
A
P
D
E
K
Y
V
A
A
K
I
R
T
Dog
Lupus familis
XP_531803
727
83861
Y169
R
V
A
P
D
E
K
Y
V
A
A
K
I
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8C167
725
83176
Y167
R
V
A
P
D
E
K
Y
V
A
A
K
I
R
T
Rat
Rattus norvegicus
Q5HZA6
726
83463
Y168
R
V
A
P
D
E
K
Y
V
A
A
K
I
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521562
342
37329
Chicken
Gallus gallus
Q5ZKL5
732
84295
P183
I
K
R
I
R
I
S
P
D
E
R
Y
L
A
T
Frog
Xenopus laevis
Q32N48
707
80150
K146
Q
K
I
R
V
S
P
K
Q
K
F
M
A
V
T
Zebra Danio
Brachydanio rerio
NP_001139088
692
78210
G151
C
M
L
I
R
L
N
G
V
S
C
T
Q
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780381
720
80994
A148
V
V
E
G
S
P
D
A
Y
D
G
H
I
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151599
784
87028
R188
C
R
I
S
P
D
H
R
F
L
A
Y
T
V
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
96.1
N.A.
90.9
90.3
N.A.
26.5
47.5
42
37.9
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.7
99.5
98.3
N.A.
95
94.7
N.A.
34.5
66.6
61.4
54.8
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
0
6.6
6.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
0
13.3
13.3
26.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
9
0
50
59
0
9
9
9
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
50
9
9
0
9
9
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
50
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% H
% Ile:
9
0
17
17
0
9
0
0
0
0
0
0
59
9
0
% I
% Lys:
0
17
0
0
0
0
50
9
0
9
0
50
0
0
9
% K
% Leu:
0
0
9
0
0
9
0
0
0
9
0
0
9
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
50
9
9
9
9
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% Q
% Arg:
50
9
9
9
17
0
0
9
0
0
9
0
0
59
0
% R
% Ser:
0
0
0
9
9
9
9
0
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
59
% T
% Val:
9
59
0
0
9
0
0
0
59
0
0
0
0
17
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
9
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _